Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. However, if you're taking prescription medication, talk to your pharmacist or primary care provider about potential flaxseed oil drug interactions first. View abstract. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Dietary lignans and postmenopausal breast cancer risk by oestrogen receptor status: a prospective cohort study of Swedish women. View abstract. Chavarro JE, Stampfer MJ, Li H, et al. View abstract. Medically reviewed by Drugs.com on Jul 25, 2022. Similar to any other medication, Trulicity (dulaglutide) may interact with certain drugs or health conditions. Even though it's just a food, flaxseed oil may not mix well with certain health conditions or medications. Natural Medicines. May cause allergic reactions. Flaxseed oil is a supplement that can boost your intake of omega-3 fatty acids. View abstract. The evidence is mixed as to whether flaxseed or flaxseed oil has any effect on the prostate or the risk of prostate cancer. Flaxseed oil, the most commonly used high risk supplement that contains phosphorus, was taken by 16 percent of patients with normal or mildly reduced kidney function. Flax is often sold as an herbal supplement. Patade A, Devareddy L, Lucas EA, et al. Hypertension. Although not all side effects are known, flax is thought to be likely safe for most people when taken by mouth. Cotterchio M, Boucher BA, Kreiger N, et al. Advertising revenue supports our not-for-profit mission. Cancer Epidemiol Biomarkers Prev 2000;9:719-25. Ultimately, if flaxseed is to blame, an upped dosage of levothyroxine medication is probably needed going further. Int J Cancer 2006;119:925-31. Call your doctor for medical advice about side effects. 5 Science-Based Benefits of 5-HTP (Plus Dosage and Side Effects), The 15 Best Vitamin Brands of 2023: A Dietitians Picks, Red Raspberry Leaf Tea: Pregnancy, Benefits, and Side Effects. All rights reserved. Certain herbal supplements, such as St. John's wort, may decrease blood levels of some statin drugs, and when taken with atorvastatin, may . View abstract. You should also discuss the length of time its healthy to use it as well as a recommended dosage. 1 Severe Side Effects Nutr Metab (Lond) 2021;18(1):91. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, There are many studies currently under way, flax seeds may increase your chances of bleeding, Interactions with medications and health conditions, nccih.nih.gov/health/flaxseed/ataglance.htm, mayoclinic.org/drugs-supplements/flaxseed-and-flaxseed-oil/background/hrb-20059416, oncologynutrition.org/erfc/healthy-nutrition-now/flaxseed-prostate-cancer-risk/, pennstatehershey.adam.com/content.aspx?productId=107&pid=33&gid=000959, mayoclinic.org/what-are-omega-3-fatty-acids-from-fish-oil/art-20232583, health.harvard.edu/heart-health/why-not-flaxseed-oil, 6 Benefits of Flaxseed Oil Plus How to Use It. View abstract. Natural Medicines. 2014;22:43. WebMD does not provide medical advice, diagnosis or treatment. Bongartz U, Hochmann U, Grube B, et al. Dietary phytoestrogens and lung cancer risk. Bodybuilder Darwin Uribe Will Withdraw From 2023 Arnold Classic. Last medically reviewed on September 26, 2017. Chen J, Power KA, Mann J, et al. (2014). Mohammadi-Sartang M, Mazloom Z, Raeisi-Dehkordi H, Barati-Bodaji R, Bellisimo N, Totosy de Zepetnek JO. Monitor your blood pressure closely. Clin Nutr ESPEN. 1. However, you should always talk to your primary care provider to discuss flaxseed oil dosage and safety before adding the plant oil to your daily routine. Summary: Drug interactions are reported among people who take Flaxseed and Metformin. 2013 Aug 1;167(8):708-13. Though tiny, they are rich in the omega-3 fatty acid ALA, lignans and fiber, all of which have been shown to have many potential health . Urology 2004;63:900-4.. View abstract. Flax seeds are considered to help with constipation. How fast does psyllium work? Flaxseed and flaxseed oil (Linum usitatissimum). Cancer Epidemiol Biomarkers Prev 2000;9:335-8. However, research has shown that flax may not be effective in treating this condition. Available for Android and iOS devices. Other drugs may interact with flax, including prescription and over-the-counter medicines, vitamins, and herbal products. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. This means that flaxseed can help improve digestion and lower cholesterol levels, while flaxseed oil does not have these effects. View abstract. Examples of barbiturates and medications that have barbiturate actions include: Felbatol (felbamate) Lucas EA, Wild RD, Hammond LJ, et al. 2013;23(6):446-7. Do not use extra flax to make up the missed dose. Flaxseeds are high in potassium. De Stefani E, Deneo-Pellegrini H, Boffetta P, et al. Can J Physiol Pharmacol. Thompson LU, Chen JM, Li T, et al. Mammalian lignans inhibit the growth of estrogen-independent human colon tumor cells. J Natl Cancer Inst 1999;91:414-28. Yes: Flaxseed may interact with acetaminophen, certain antibiotics, estrogens, furosemide, Ketoprofen, diabetes medication, anticoagulants & Metoprolo. Raspberries - joint pain. A total of 12 drugs are known to interact with green tea. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Kuijsten A, Arts IC, Hollman PC, et al. Taking flaxseed by mouth seems to help reduce, Breast pain (mastalgia). Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer. While some studies support health claims, most are small, and more research is needed. Circulating enterolactone and risk of endometrial cancer. Health aspects of fish and n-3 polyunsaturated fatty acids from plant and marine origin. You may be eager to find a supplement to boost the omega-3 fatty acids in your body. Clin Rheumatol. Demark-Wahnefried W, Price DT, Polascik TJ, et al. Haggans CJ, Hutchins AM, Olson BA, et al. View abstract. Giovannucci E, Rimm EB, Colditz GA, et al. Finnegan YE, Minihane AM, Leigh-Firbank EC, et al. Dietary intake of n-3 and n-6 fatty acids and the risk of prostate cancer. View abstract. Yang C, Xia H, Wan M, et al. Clin Cancer Res 2004;10:7703-11. Chen J, Wang L, Thompson LU. Flaxseed supplementation in hyperlipidemic patients. View abstract. 2020:1-9. View abstract. Atherosclerosis 1997;132:69-76. This information may not fit your specific health circumstances. Flaxseed oil is an oil made from pressed, ground flaxseeds. These might be signs of anaphylactic shock. View abstract. Goss PE, Li T, Theriault M, et al. Fish oil may be a better and safer choice. J Nutr 2010;140:1937-42. Written by Cerner Multum. Use caution when adding flaxseed oil to your diet or using it as a supplement. The effect of flaxseed supplementation on the initiation and promotional stages of mammary tumorigenesis. 2021;75(1):99-111. information and will only use or disclose that information as set forth in our notice of J Nutr 2010;140:293-7. Flaxseed (Linum usitatissimum) and flaxseed oil, which comes from flaxseed, are rich sources of the essential fatty acid alpha-linolenic acid a heart-healthy omega-3 fatty acid. We'll take a look at just what makes hemp oil beneficial and which conditions may improve from. The side effects of flaxseed oil may lead to adverse reactions if you consume it and take certain medications or have particular medical conditions. You should discontinue and avoid the use of flaxseed oil if you notice itching, swelling, redness, or hives when you ingest it. Answer: Atorvastatin (Lipitor), rosuvastatin (Crestor), and other cholesterol-lowering statin drugs can be affected by taking supplements and can affect your ability to absorb certain vitamins and minerals. Breast Cancer Res Treat 2000;64:49. Drink plenty of water each day while you are taking this product. Saw palmetto Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: Aspirin Clopidogrel Warfarin St. John's wort J Med Food 2008;11:207-14. Cancer Lett 1991;60:135-42. Cancer Epidemiol Biomarkers Prev 2008;17:3241-51. are using cholesterol-lowering drugs. Grapefruit and their products contain a natural chemical that interfere with the break down of certain medications, such as simvastatin and atorvastatin. All rights reserved. List Flaxseed side effects by likelihood and severity. Saarinen NM, Power K, Chen J, Thompson LU. The effectiveness of your oral contraceptives or hormonal therapy may also be affected by flaxseed meal consumption. J Med Food 2012;15:840-5. Most of the animal studies have focused on breast cancer. (2016). Cotterchio M, Boucher BA, Manno M, et al. Polypodium Leucotomos - Inotersen. Do not take this medication for more than 7 days unless directed by your doctor. View abstract. View abstract. Lifestyle counseling and supplementation with flaxseed or walnuts influence the management of metabolic syndrome. Khandouzi N, Zahedmehr A, Mohammadzadeh A, Sanati HR, Nasrollahzadeh J. 2019;29:41-48. Pan A, Sun J, Chen Y, et al. J Womens Health (Larchmt) 2008;17:355-66. Flaxseed is packed with beneficial nutrients, omega-3 fatty acids, and fiber. Savas BB, Alparslan GB, Korkmaz C. Effect of flaxseed poultice compress application on pain and hand functions of patients with hand osteoarthritis. The effect of flaxseed powder on insulin resistance indices and blood pressure in prediabetic individuals: a randomized controlled clinical trial. View abstract. Keep in mind the FDA does not recommend Trulicity as a "first-line therapy" for . Flaxseed attenuates the tumor growth stimulating effect of soy protein in ovariectomized athymic mice with MCF-7 human breast cancer xenografts. Comparisons of the effects of different flaxseed products consumption on lipid profiles, inflammatory cytokines and anthropometric indices in patients with dyslipidemia related diseases: systematic review and a dose-response meta-analysis of randomized controlled trials. Haggans CJ, Travelli EJ, Thomas W, et al. When taken in the right doses and in the short term, flaxseed oil is usually safe for most adults. Follow your healthcare provider's instructions about any restrictions on food, beverages, or activity. Nesbitt PD, Lam Y, Thompson LU. Discuss with your doctor the benefits of flaxseed oil for your health before trying it out. View abstract. Yari Z, Cheraghpour M, Alavian SM, Hedayati M, Eini-Zinab H, Hekmatdoost A. Even though the nutritional profile of flaxseeds may be useful for improving the function of the Thyroid, it is important to consider that there is also one particular concerning the fact that need to be taken into account. Kilkkinen A, Stumpf K, Pietinen P, et al. View abstract. Daily flaxseed consumption improves glycemic control in obese men and women with pre-diabetes: a randomized study. Effects of linseeds on the symptoms of irritable bowel syndrome: a pilot randomised controlled trial. Flaxseed can act like a laxative. Sometimes flax seed will interfere with the absorption of other medications. Some people use black seed oil supplements to treat certain health conditions, including arthritis, allergies, asthma, and diabetes, and maintain a healthy weight. Fact Checked by Paul Bossung. Taylor, C. G., Noto, A. D., Stringer, D. M., Froese, S., and Malcolmson, L. Dietary milled flaxseed and flaxseed oil improve N-3 fatty acid status and do not affect glycemic control in individuals with well-controlled type 2 diabetes. 1995;49(3):169-178. View abstract. Flaxseed is also taken by mouth for acne, attention deficit-hyperactivity disorder (ADHD), kidney problems in people with a disease called systemic lupus erythematosus (SLE), symptoms of menopause, breast pain, diabetes, obesity and weight loss, HIV/AIDS, depression, malaria, rheumatoid arthritis, sore throat, upper respiratory tract infections This means that flaxseed can help improve digestion and lower cholesterol levels, while flaxseed oil does not have these effects. 2018 Feb 1;76(2):125-39. WebMD does not provide medical advice, diagnosis or treatment. Hadi A, Askarpour M, Salamat S, Ghaedi E, Symonds ME, Miraghajani M. Effect of flaxseed supplementation on lipid profile: An updated systematic review and dose-response meta-analysis of sixty-two randomized controlled trials. Do not use this product without medical advice if you are breast-feeding a baby. Nutr Cancer 1992;17:153-9. View abstract. https://nccih.nih.gov/health/flaxseed/ataglance.htm. Use this medication regularly to get the most benefit from it. Before using flax, talk to your healthcare provider. Flaxseed oil may be rich in omega-3 fatty acids, but it may not be the right type. Taking flaxseed along with medications that lower blood pressure might cause blood pressure to go too low. Int J Cancer 2006;119:2376-81. View abstract. Nutr Cancer 1999;33:188-95. View abstract. Caligiuri SP, Aukema HM, Ravandi A, Guzman R, Dibrov E, Pierce GN. Oncology Nutrition advises that you should discuss the use of flax seeds with your doctor and avoid the use of flaxseed oil altogether because it provides no benefit to those with prostate cancer. Koizumi Y, Arai H, Nagase H, Kano S, Tachizawa N, Sagawa T, Yamaguchi M, Ohta K. [Case report: anaphylaxis caused by linseed included in baked bread]. Flaxseed oil is generally cold pressed. Am J Clin Nutr 1995;61:62-8. J Clin Endocrinol Metab 2002;87:1527-32.. View abstract. Menopause 2012;19:48-53. Anticoagulant and anti-platelet drugs, herbs and supplements. No related drugs found for this medication. Supplementation with flaxseed alters estrogen metabolism in postmenopausal women to a greater extent than does supplementation with an equal amount of soy. Using different formulations together increases the risk of an overdose. View abstract. Phytother Res 2021;35(7):3781-3791. Fink BN, Steck SE, Wolff MS, et al. However, it requires a steady dose of essential nutrients, which must come from food or supplements, in order to function at its best. Epiandrosterone . Adolescent dietary phytoestrogen intake and breast cancer risk (Canada). Rickard SE, Yuan YV, Thompson LU. Flax seed oil is in the drug class herbal products. When taken in recommended amounts, flaxseed and flaxseed oil are generally safe to use. View abstract. Do not take flax without medical advice if you are using any of the following medications: any medications for diabetes or high blood pressure; This list is not complete. Flaxseed has most often been used by adults in doses of 20-30 grams by mouth daily. Information from this source is evidence-based and objective, and without commercial influence. View abstract. This content does not have an English version. Goyal A, et al. View abstract. J Am Coll Nutr 2010;29(1):72-80. Flaxseed is an herbal supplement used to treat constipation (chronic), enlarged prostate (oil), cancer (prevention), diabetes, diverticulitis, inflammation of the small intestine and/or the stomach, high cholesterol, irritable bowel syndrome, menopausal symptoms, myocardial infarction prevention (oil), skin inflammation, and systemic lupus Carcinogenesis 1996;17:1373-6. Int J Prev Med. Allergol Immunopathol (Madr) 2003;31:47-9. . Cancer Causes Control 2008;19:259-72. PAF is an active compound in the body that is related to a variety of immunological reactions. Refrigerated flaxseed should be used within 30 days of being ground, and frozen flaxseed should be used within 45 days of storing. Wu H, Pan A, Yu Z, et al. However, when taken in large amounts and with too little water, flaxseed can cause: Avoid use of flaxseed and flaxseed oil during pregnancy. What should I know regarding pregnancy, nursing and administering Flaxseed to children or the elderly. Touillaud MS, Thiebaut AC, Fournier A, et al. View abstract. The authors of the article in the Journal of Food Science and Technology call flaxseed oil a functional food because of its potential health benefits. Bloedon LT, Szapary PO. View abstract. View abstract. Flax and flaxseed oil: An ancient medicine and modern functional food. The omega-3 supplement may increase your fasting blood sugar levels and decrease the effectiveness of your diabetes medication. Possible side effects include: Diarrhea and loose stools Worsening constipation 1 These side effects can be minimized by taking flaxseed oil with plenty of water and by taking it at recommended doses. This will help prevent any negative reactions that might arise. Flaxseed consumption reduces blood pressure in patients with hypertension by altering circulating oxylipins via an a-linolenic acid-induced inhibition of soluble epoxide hydrolase. Leon F, Rodriguez M, Cuevas M. Anaphylaxis to Linum.
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